6533b820fe1ef96bd1279b97

RESEARCH PRODUCT

Analysis and evaluation of periodic physiological organ motion in radiotherapy treatments.

Francisco SendraSergio DíezJavier Garcia

subject

medicine.medical_specialtymedicine.medical_treatmentMovementRespiratory SystemPlanning target volumeProbability density functionPatient Care PlanningAutomationOrgan MotionPosition (vector)NeoplasmsMedicineHumansRadiology Nuclear Medicine and imagingComputer visionbusiness.industryMatched filterRespirationHematologySurgeryRadiation therapyOncologyFluoroscopyRadiotherapy treatmentArtificial intelligenceDose Fractionation RadiationRadiotherapy Conformalbusiness

description

Background and purpose: A system for the detection, measurement and analysis of the periodic physiological organ motion during radiotherapy treatment is proposed and clinically tested in this paper. Material and methods: The procedure is based on the acquisition of fluoroscopic sequences, followed by an automatic detection of the movement using cross-correlations with matched filters. Results: The system generates a probability density function (PDF) of finding a mobile organ in a position at a certain time. The maximum path of the mobile structures can be determined to define the planning target volume (PTV) without ambiguities. Conclusions: Physiological movements can be accurately included in the daily planning routine, which is not essentially modified, without needing previous patient training. q 2004 Elsevier Ireland Ltd. All rights reserved.

10.1016/j.radonc.2004.08.023https://pubmed.ncbi.nlm.nih.gov/15588878