6533b820fe1ef96bd1279cea
RESEARCH PRODUCT
A quantitative study of substituent effects on oxidative cyclization of some 2-aryl-substituted aldehyde thiosemicarbazones induced by ferric chloride and cupric perchlorate
Michelangelo GruttadauriaRenato NotoGiuseppe WerberPaolo Lo Meosubject
chemistry.chemical_classificationOxidative cyclizationChemistryArylOrganic ChemistrySubstituentChlorideAldehydeMedicinal chemistrychemistry.chemical_compoundPerchloratemedicineFerricmedicine.drugdescription
As a development of our previous work, we performed a kinetic study of the oxidative cyclization reaction of some 2,4-diaryl-substituted aldehyde thiosemicarbazones 1a-n induced by ferric chloride and by cupric perchlorate. The results of cyclization of 1a-n were compared to those of the corresponding 2-methyl derivatives. The kinetic data were analyzed by means of the Hammett's equation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1999-05-01 |