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RESEARCH PRODUCT
1H, 13C, 15N NMR, ESI mass spectral and single crystal X-ray structural characterization of three spiro[pyrrolidine-2,3′-oxindoles]
Arto ValkonenErkki KolehmainenAlexander S. AntonovKatri LaihiaI. FedosovVladimir NikiforovD. Zhukovsubject
Chemical shiftOrganic ChemistryAnalytical chemistryPyrrolidineSpectral lineAnalytical ChemistryInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryHeteronuclear moleculePulsed field gradientTwo-dimensional nuclear magnetic resonance spectroscopySingle crystalSpectroscopyMonoclinic crystal systemdescription
Abstract Three spiro[pyrrolidine-2,3′-oxindoles], 1,1′,2,2′,5′,6′,7′,7′a-octahydro-2-oxo-1′-phenyl-spiro[3H-indole-3,3′-[3H]-pyrrolizine]-2′-carboxylic acid methyl ester (1), 1,1′,2,2′,5′,6′,7′,7′a-octahydro-2-oxo-1′-nitro-2′-phenyl-spiro[3H-indole-3, 3′-[3H]-pyrrolizine] (2) and 1,1′,2,2′,5′,6′,7′,7′a-octahydro-2-oxo-1′-nitro-2′-(4″-chlorophenyl)-spiro[3H-indole-3,3′-[3H]-pyrrolizine] (3) have been synthesized and their 1H, 13C and 15N spectra assigned. The chemical shift assignments are based on Pulsed Field Gradient (PFG) Double Quantum Filter (DQF) 1H, 1H correlation spectroscopy (COSY), PFG 1H, 13C Heteronuclear Multiple Quantum Coherence (HMQC) and PFG 1H,X (X = 13C and 15N) Heteronuclear Multiple Bond Correlation (HMBC) experiments. The single crystal X-ray structures of 1–3 have been determined. Compounds 1 and 2 crystallized in monoclinic space group C2/c and compound 3 in monoclinic space group P21/c, respectively. Also the ESI-TOF MS data of 1–3 are given.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-12-01 | Journal of Molecular Structure |