6533b820fe1ef96bd127a47d

RESEARCH PRODUCT

Novel recombinant GII.P16_GII.13 and GII.P16_GII.3 norovirus strains in Italy.

Vito MartellaMaria Cristina ArcangelettiSimona De GraziaCarlo ChezziAdriana CalderaroFlora De ContoFabio TummoloMaria Cristina MediciGiovanni M. Giammanco

subject

Cancer ResearchSettore MED/07 - Microbiologia E Microbiologia ClinicaGenotypevirusesMolecular Sequence DataBiologymedicine.disease_causelaw.inventionfluids and secretionslawVirologymedicineCluster AnalysisHumansGenePhylogenyCaliciviridae InfectionsRecombination GeneticNoroviruPhylogenetic treeGastroenteritiNorovirusvirus diseasesOutbreakGII.P16_GII.3InfantSequence Analysis DNAVirologyRecombinationGastroenteritisInfectious DiseasesCapsidItalyChild PreschoolRecombinant DNANorovirusRNA ViralCapsid ProteinsGII.P16_GII.13

description

Novel norovirus strains are continuously emerging worldwide. Molecular investigation and phylogenetic analysis identified GII.P16 recombinant noroviruses from the stools of four Italian children with gastroenteritis. The capsid gene was characterized as either GII.13 or GII.3. The GII.P16_GII.13 Italian strains were closely related to German strains involved in a large outbreak in the second half of 2012 and the Italian strains are the first recorded occurrence of GII.P16_GII.13 in Europe.

10.1016/j.virusres.2014.04.005https://pubmed.ncbi.nlm.nih.gov/24751799