6533b820fe1ef96bd127a4b2

RESEARCH PRODUCT

Unusual oleanane-type saponins from Arenaria montana

Jean Franois MirjoletAnne Claire Mitaine-offerGaoussou TimitéMarie Aleth Lacaille-duboisChiaki TanakaTomofumi MiyamotoOlivier Duchamp

subject

Arenaria montanaMagnetic Resonance SpectroscopyStereochemistryChemical structureArenaria PlantSaponinCaryophyllaceaeAntineoplastic AgentsPlant ScienceHorticultureMass spectrometryBiochemistryMass Spectrometrychemistry.chemical_compoundCell Line TumorBotanyHumansOleanolic AcidMolecular BiologyOleananeCell Proliferationchemistry.chemical_classificationDose-Response Relationship DrugMolecular StructurebiologyStereoisomerismGeneral MedicineSaponinsbiology.organism_classificationchemistryDrug Screening Assays AntitumorEchinocystic acidTwo-dimensional nuclear magnetic resonance spectroscopy

description

Three oleanane-type saponins, 3-O-β-d-glucopyranosylechinocystic acid 28-O-β-d-xylopyranosyl-(1→4)-[α-l-rhamnopyranosyl-(1→2)]-α-l-rhamnopyranosyl ester (1), 3-O-β-d-glucopyranosylechinocystic acid 28-O-α-l-arabinopyranosyl-(1→3)-β-d-xylopyranosyl-(1→4)-[α-l-rhamnopyranosyl-(1→2)]-α-l-rhamnopyranosyl ester (2), 3-O-β-d-glucopyranosylcaulophyllogenin 28-O-β-d-apiofuranosyl-(1→3)-β-d-xylopyranosyl-(1→4)-[β-d-apiofuranosyl-(1→3)]-α-l-rhamnopyranosyl-(1→2)-α-l-rhamnopyranosyl ester (3) were isolated from the whole plant of Arenaria montana. Their unusual structures for the Caryophyllaceae family were established mainly by 2D NMR techniques and mass spectrometry.

yearjournalcountryeditionlanguage
2010-11-19Phytochemistry
https://doi.org/10.1016/j.phytochem.2011.01.011