6533b821fe1ef96bd127acf3

RESEARCH PRODUCT

Short Ammonium Chloride Loading Test for Evaluation of Hyperparathyroidism

Peter Alken

subject

Ammonium chloride loading testHyperparathyroidismmedicine.medical_specialtyStone patientNeck explorationbusiness.industrymedicineUrologymedicine.diseasebusinessParathyroid adenoma

description

The dilemma in the diagnosis of hyperparathyroidism (HPT) is reflected by three factors: Hypercalcemia is still regarded as the most important diagnostic sign, but unless multiple determinations of serum calcium are done, the so-called borderline cases will be missed. Tests that readily identify HPT combine either simple performance, widespread use and low accuracy (CP, TRP, PEI, TMP/GFR)l or sophisticated methods, limited use and high accuracy (PTH, Ca+++, c-AMP). Consequently, some authors perform neck explorations to cure patients with recurrent nephrolithiasis who do not fulfill the diagnostic criteria of HPT. However, the stone recurrence rate may then reach 75%2,3 In this situation, to complete the diagnostic puzzle of hyperparathyroidism additional information is valuable.

yearjournalcountryeditionlanguage
1981-01-01
https://doi.org/10.1007/978-1-4684-8977-4_17