6533b821fe1ef96bd127ad31
RESEARCH PRODUCT
One-step synthesis of resorcarene dimers composed of two tetra-benzoxazine units
Iris ThondorfKari RissanenChristian SchmidtWalter VogtVolker Bo¨hmerErkki Kolehmainensubject
biologyDimerOrganic ChemistryEthylenediamineResorcinarenebiology.organism_classificationBiochemistrychemistry.chemical_compoundchemistryDrug DiscoveryPolymer chemistryMass spectrumProton NMROrganic chemistryTetraMoleculeAmine gas treatingdescription
Abstract The condensation of resorcarene 1 with ethylenediamine and an excess of formaldehyde gives, under high dilution conditions, in up to 15% yield the octa-benzoxazine dimer 2 in which two molecules of 1 are connected by four bridges. The structure of 2 has been confirmed by 1 H NMR spectra and MALDI-TOF mass spectra and by hydrolysis of the oxazine rings yielding the secondary amine 3 .
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1998-11-01 | Tetrahedron Letters |