Antithrombotic Therapy in Elderly Patients with Acute Coronary Syndromes

6533b821fe1ef96bd127af45

RESEARCH PRODUCT

Antithrombotic Therapy in Elderly Patients with Acute Coronary Syndromes

Clara Bonanad Francisca Esteve-claramunt Sergio García-blas Ana Ayesta Pablo Díez-villanueva Jose-ángel Pérez-rivera José Luis Ferreiro Joaquim Cánoves Francisco López-fornás Albert Ariza Solé Sergio Raposerias David Vivas Regina Blanco Daznia Bompart Berroterán Alberto Cordero Julio Núñez Lorenzo Fácila Iván J. Núñez-gil José Luis Górriz Vicente Bodí Manuel Martínez-sellés Juan Miguel Ruiz Nodar Francisco Javier Chorro

subject

clopidogrel Heart diseases Gerontología Enfermedad cardiovascular General Medicine Cardiología Clorhidrato de prasugrel elderly antiplatelet therapy Malalties del cor acute coronary syndrome prasugrel ticagrelor Anticoagulants (Medicina)Síndrome coronario agudo Anticoagulants (Medicine)

description

The treatment of acute coronary syndrome (ACS) in elderly patients continues to be a challenge because of the characteS.G.B.ristics of this population and the lack of data and specific recommendations. This review summarizes the current evidence about critical points of oral antithrombotic therapy in elderly patients. To this end, we discuss the peculiarities and differences reported referring to dual antiplatelet therapy (DAPT) in ACS management in elderly patients and what might be the best option considering these population characteristics. Furthermore, we analyze antithrombotic strategies in patients with atrial fibrillation (AF), with a particular focus on those cases that also present coronary artery disease (CAD). It is imperative to deepen our knowledge regarding the management of these challenging patients through real-world data and specifically designed geriatric studies to help resolve the questions remaining in their disease management. Instituto de Salud Carlos III / FEDER Founds (JR/21/00041, CIBERCV16/11/00486, PI20/00637) Generalitat Valencia, Conselleria d'Educació (PROMETEO/21/008) 4.242 JCR (2020) Q1, 39/167 Medicine, General & Internal 1.040 SJR (2021) Q1, 438/2489 Medicine (miscellaneous) No data IDR 2020 UEV

year	journal	country	edition	language
2022-05-26

10.3390/jcm11113008 https://eprints.ucm.es/id/eprint/73354/1/jcm-11-03008.pdf

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