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RESEARCH PRODUCT
Cerebellum and Prematurity: A Complex Interplay Between Disruptive and Dysmaturational Events.
Gabriella Di RosaAnna CafeoGiulia SpotoAntonio Gennaro NicoteraGiuseppe QuatrosiGreta AmoreLuigi VetriEloisa Gittosubject
CerebellumCognitive NeuroscienceNeuroscience (miscellaneous)Neurosciences. Biological psychiatry. NeuropsychiatryReviewThird trimestercerebellar underdevelopment03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineDevelopmental Neuroscience030225 pediatricsmedicinecerebellar hemorrhage; cerebellar infarction; cerebellar underdevelopment; cerebellum and neurodevelopment; early intervention; prematurityCerebellar infarctionPregnancybusiness.industryprematurityCognitionDeveloping cerebellummedicine.diseasecerebellar hemorrhageMotor coordinationcerebellum and neurodevelopmentearly interventionmedicine.anatomical_structurenervous systemCerebellar hemorrhagebusinessNeurosciencecerebellar infarction030217 neurology & neurosurgeryNeuroscienceRC321-571description
The cerebellum plays a critical regulatory role in motor coordination, cognition, behavior, language, memory, and learning, hence overseeing a multiplicity of functions. Cerebellar development begins during early embryonic development, lasting until the first postnatal years. Particularly, the greatest increase of its volume occurs during the third trimester of pregnancy, which represents a critical period for cerebellar maturation. Preterm birth and all the related prenatal and perinatal contingencies may determine both dysmaturative and lesional events, potentially involving the developing cerebellum, and contributing to the constellation of the neuropsychiatric outcomes with several implications in setting-up clinical follow-up and early intervention.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-06-01 |