6533b821fe1ef96bd127b005

RESEARCH PRODUCT

In vitro release of lectins by Phallusia mamillata hemocytes.

Vincenzo ArizzaNicolò ParrinelloSandra Schimmenti

subject

PhallusiaAmanitinsHemocytesHemocyteImmunologyBiologyTunicateLectinsAnimalsUrochordataCycloheximideCells Culturedchemistry.chemical_classificationLectinActive proteinbiology.organism_classificationIn vitroCulture MediaBiochemistrychemistryReleasebiology.proteinDactinomycinLiberationGlycoproteinSecretory RateLectinDevelopmental Biology

description

Abstract α-Lactose specific lectins are released from Phallusia mamillata hemocytes during short-term cultures. The molecular weight of the subunits, the immunological cross-reaction and the sugar specificity suggest that the released lectins are similar to those isolated from the sonicated hemocytes. Because lectin release appears to take place independently of active protein synthesis, the possibility exists that lectins are pre-formed, stored in hemocytes and released when in vitro conditions stimulate the cells.

10.1016/0145-305x(91)90015-qhttps://pubmed.ncbi.nlm.nih.gov/1773847