6533b821fe1ef96bd127b885
RESEARCH PRODUCT
A Simple Entropic-Driving Separation Procedure of Low-Size Silver Clusters, Through Interaction with DNA
Fernando DomínguezSara VieitezDavid BucetaBlanca DominguezM. Arturo López-quintelaJ. Manuel AgeitosM. Carmen BlancoGiampaolo BaroneIria R. Ariassubject
SilverResearch areasEntropyDna interactionIntercalation (chemistry)silver clustersMetal NanoparticlesChemical Fractionationchemistry.chemical_compoundseparation proceduresQD1-999Strong bindingmass spectrometryChemistryCommunicationentropically-driven processesGeneral ChemistryDNAIntercalating AgentsCommunicationsDNA interactionChemistryChemical physicsSettore CHIM/03 - Chimica Generale E InorganicaDialysis (biochemistry)DNAMetal clustersSeparation proceduredescription
Abstract Synthesis and purification of metal clusters without strong binding agents by wet chemical methods are very attractive for their potential applications in many research areas. However, especially challenging is the separation of uncharged clusters with only a few number of atoms, which renders the usual techniques very difficult to apply. Herein, we report the first efficient separation of Ag2 and Ag3 clusters using the different entropic driving forces when such clusters interact with DNA, into which Ag3 selectively intercalates. After sequential dialysis of the samples and denaturalizing the DNA‐Ag3 complex, pure Ag2 can be found in the dialysate after extensive dialysis. Free Ag3 is recovered after DNA denaturation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-08-01 |