6533b821fe1ef96bd127b9f6
RESEARCH PRODUCT
Synthesis and characterization of new polyamino-cyclodextrin materials.
Paolo Lo MeoMichelangelo GruttadauriaRenato NotoSerena RielaFrancesca D'annasubject
Potentiometric titrationSilverPotentiometric titrationMetal NanoparticlesChemistry Techniques SyntheticBiochemistrySilver nanoparticleAnalytical ChemistryMetalchemistry.chemical_compoundPolarimetryOrganic chemistryAmineschemistry.chemical_classificationCyclodextrinsAniline CompoundsCyclodextrinModified cyclodextrinOrganic ChemistrySettore CHIM/06 - Chimica OrganicaGeneral MedicineGene transfectionESI-MS mass spectrometryCharacterization (materials science)chemistryvisual_artvisual_art.visual_art_mediumSilver nanoparticlesPolyaminedescription
With the aim of the synthesis of chemically modified cyclodextrins bearing polyamine pendant groups, potentially useful as capping agents for the preparation of nanosized metal systems or as auxiliaries for gene transfection, the reaction between the heptakis-(6-iodo)-(6-deoxy)-b-cyclodextrin and various polyamines has been explored. This synthetic approach allows obtaining materials constituted by mixtures of cyclodextrins, having different degrees of substitution, which were satisfactorily characterized by means of various complementary techniques (ESI-MS, NMR, potentiometric titration). The products obtained were successfully subjected to preliminary tests for their binding abilities towards suitable organic guests and as capping agents for the preparation of stable silver nanoparticles.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-08-01 | Carbohydrate research |