6533b821fe1ef96bd127ba9d
RESEARCH PRODUCT
Respiratory gas exchange in the rat spleen in situ and intrasplenic oxyhemoglobin saturation.
Peter VaupelW. Müller-klieserR. Manzsubject
In situMalemedicine.medical_specialtyErythrocytesPhysiologyClinical BiochemistryRespiratory gas exchangeSpleenOxygen ConsumptionPhysiology (medical)Internal medicinemedicineAnimalsOxyhemoglobin saturationChemistryHuman physiologyHypoxia (medical)RatsEndocrinologymedicine.anatomical_structureOxyhemoglobinsImmunologyRed pulpRat SpleenFemalemedicine.symptomSpleendescription
Measurements of splenic respiratory gas exchange and of HbO2 saturations in the red pulp of the rat spleen have shown that there are no indications of a reduced intrasplenic O2 availability during normoxia. The present studies provide evidence that, in the normal spleen, the intrasplenic sequestration of red blood cells cannot be explained by an O2 deficiency in the red pulp since the commonly accepted notion of an intrasplenic hypoxia is not true.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1979-02-01 | Pflugers Archiv : European journal of physiology |