6533b821fe1ef96bd127bdd3
RESEARCH PRODUCT
The PCSK9 gene: a new gene controlling cholesterolemia
Ab CefaluS AmatoE FertittaF FayerV ValentiMc GueliU Di BlasiM PaganoIb NardiG CusumanoP GulottaA RaffaT DoveriM Avernasubject
PCSK9Settore MED/09 - Medicina Internahypercholesterolemiamutationdescription
The distribution of cholesterol plasma is regulated by complex interactions between genes and environmental factors. Mutations of PCSK9 gene seem to modulate the levels of LDLC. Mutations of PCSK9 gene with gain of function are associated to hypercholesterolemia and mutations with loss of function determine hypocholesterolemia.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-01-01 |