Case report: necrotizing fascitis of odontogenenic origin in a subject affected by uncompensated type 2 diabetes mellitus

The PCSK9 gene: a new gene controlling cholesterolemia

The distribution of cholesterol plasma is regulated by complex interactions between genes and environmental factors. Mutations of PCSK9 gene seem to modulate the levels of LDLC. Mutations of PCSK9 gene with gain of function are associated to hypercholesterolemia and mutations with loss of function determine hypocholesterolemia.