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RESEARCH PRODUCT
Flow-injection spectrofluorimetric determination of paracetamol
J. Martínez CalatayudC. Gómez Benitosubject
AnalyteChromatographyChemistryPotassiumdigestive oral and skin physiologyRelative standard deviationFluorescence spectrometrychemistry.chemical_elementInjection rateBiochemistryAnalytical ChemistryEnvironmental ChemistryQuantitative analysis (chemistry)Spectroscopydescription
Abstract A flow-injection spectrofluorimetric determination of paracetamol is reported, based on the oxidation of the analyte with potassium hexacyanoferrate(III) immobilized on an anion-exchange resin, the fluorescence being enhanced with N,N′-dimethylformamide. Concentrations of paracetamol in the range 0.04–17.60 mg l−1 are determined with a relative standard deviation of 1.5%. The injection rate is 25 samples h−1. The influence of foreign species and the determination of paracetamol in several pharamaceutical formulations are also reported.
year | journal | country | edition | language |
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1990-01-01 | Analytica Chimica Acta |