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RESEARCH PRODUCT
Evaluation of Risk Stratification Markers and Models in Acute Pulmonary Embolism: Rationale and Design of the MARS-PE (Mainz Retrospective Study of Pulmonary Embolism) Study Programme
Johannes BeuleWolfgang DippoldKarsten KellerJörn O. Balzersubject
AdultDiagnostic ImagingMalemedicine.medical_specialtypulmonary embolismlcsh:Medicinerisk stratification030204 cardiovascular system & hematologyRisk AssessmentSeverity of Illness Index03 medical and health sciences0302 clinical medicinestudy designRisk FactorsGermanyMedicineHumansIn patientIntensive care medicineAgedRetrospective Studiesbusiness.industrylcsh:RRetrospective cohort studyImaging ProceduresGeneral MedicineMiddle Agedmedicine.diseasePulmonary embolism030228 respiratory systemResearch DesignRisk stratificationAcute DiseaseoutcomeTreatment strategysymptomsFemaleHemodynamic stabilitybusinessBiomarkersdescription
An acute pulmonary embolism (PE) is a crucial event in patients’ life and connected with serious morbidity and mortality. Regarding a high case-fatality rate, early and accurate risk-stratification is crucial. Risk for mortality and complications are closely related to hemodynamic stability and cardiac adaptations. The currently recommended risk-stratification approach is not overall simple to use and might delay the identification of those patients, who should be monitored more closely and may treated with more aggressive treatment strategies. Additionally, some risk-stratification criteria for the imaging procedures are still imprecise. Summarized, the search for the most effective risk-stratification tools is still ongoing and some diagnostic criteria might have to be refined. In the MAinz Retrospective Study of Pulmonary Embolism (MARS-PE), overall 182 consecutive patients with confirmed PE were retrospectively included over a 5-year period. Clinical, echocardiographic, functional and laboratory parameters were assessed. The study was designed to provide answers to some of the mentioned relevant questions.
year | journal | country | edition | language |
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2018-12-14 | Acta Medica |