6533b822fe1ef96bd127cb10

RESEARCH PRODUCT

Prenylated isoflavones from the stem bark of Erythrina sacleuxii

Ishmael B. MasesaneAnja SchüfflerTill OpatzJapheth O. OmbitoGomotsang BojaseRunner R. T. Majinda

subject

Eremothecium corylibiologyTraditional medicine010405 organic chemistryRhizomucor mieheiPratenseinPlant ScienceIsoflavonesbiology.organism_classification01 natural sciencesBiochemistry0104 chemical sciencesBiochanin A010404 medicinal & biomolecular chemistrychemistry.chemical_compoundchemistryPenicilliumErythrina sacleuxiiAgronomy and Crop ScienceBiotechnologyBotrytis cinerea

description

Abstract Two new prenylated isoflavones, named erysacleuxin A (1) and B (2), along with eight known compounds, biochanin A (3), 5′-(3-methylbut-2-enyl)pratensein (4), 7-demethylrobustigenin (5), 3′-(3-methylbut-2-enyl)biochanin A (6) abyssinone V-4′-methyl ether (7), sigmoidin E (8), erythrinasinate (9), and burtinone (10) were isolated from the stem bark of Erythrina sacleuxii Hua (Leguminosae). The structures were determined based on spectroscopic and spectrometric data. All isolated compounds were evaluated for antifungal activity against Botrytis cinerea, Candida albicans, Eremothecium coryli, Penicillium notatum, Pyricularia oryzae, and Rhizomucor miehei with compounds 3, 4 and 6 showing weak to moderate activity against P. oryzae and R. miehei.

yearjournalcountryeditionlanguage
2018-08-01Phytochemistry Letters
https://doi.org/10.1016/j.phytol.2018.05.026