6533b822fe1ef96bd127cb4a
RESEARCH PRODUCT
Chromatographic estimation of the soil-sorption coefficients of organic compounds
Salvador SagradoLaura Escuder-gilabertRosa María Villanueva-camañasJ.m. Bermúdez-saldañaMaría José Medina-hernándezsubject
ChromatographyChemical substanceChemistryAnalytical chemistrySorptionSpectroscopyAnalytical Chemistrydescription
Abstract Soil-sorption coefficient ( K OC ) assessment is essential before placing a new chemical substance on the market. Since experimental K OC measurements are tedious, time-consuming and costly, alternative approaches to estimating K OC from other descriptors have been proposed. We review the use of chromatographic retention (log k ) values, obtained in different types of chromatographic systems, as descriptors to establish predictive log K OC -log k models. We highlighted critical aspects of such models and performed a comparative study using data in the literature. We compare two strategies to deal with the large variability of experimental log K OC data. We contrast the results of this study with the main conclusions reported in the literature.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-02-01 | TrAC Trends in Analytical Chemistry |