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RESEARCH PRODUCT
Subphthalocyanines: addressing water-solubility, nano-encapsulation, and activation for optical imaging of B16 melanoma cells
Yann BernhardRémi ChassagnonPascale WincklerRichard A. DecréauElodie GigotJean-marie Perrier-cornetPhilippe Richardsubject
Models MolecularFluorescence-lifetime imaging microscopyNanostructureIndolesMelanoma ExperimentalIsoindoles010402 general chemistryPhotochemistryCrystallography X-Ray01 natural sciencesCatalysisMiceMaterials ChemistryMoleculeAnimals[CHIM]Chemical SciencesSolubilityFluorescent DyesLiposomeAqueous solutionMolecular Structure010405 organic chemistryChemistryMetals and AlloysWaterGeneral ChemistryHydrogen-Ion Concentration0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsMolecular ImagingNanostructuresNano encapsulationSolubilityLiposomesCeramics and CompositesMolecular imagingdescription
Water-soluble disulfonato-subphthalocyanines (SubPcs) or hydrophobic nano-encapsulated SubPcs are efficient probes for the fluorescence imaging of cells. 20 nm large liposomes (TEM and DLS) incorporated about 13% SubPc. Moreover, some of these fluorophores were found to be pH activatable.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-10-01 |