6533b822fe1ef96bd127cdae
RESEARCH PRODUCT
Generation of chemotactic activity by immune complexes carrying clustered or nonclustered C&42horbar; sites
R. SnydermanW. OpferkuchT. Borsossubject
Binding SitesIgm antibodyChemotaxisImmunologyCellChemotaxisAntigen-Antibody ComplexComplement System ProteinsBiologyCytotoxicity Tests ImmunologicMolecular biologyRatsImmune systemmedicine.anatomical_structureImmunologyLeukocytesmedicineAnimalsImmunology and AllergyRabbitsEdetic Aciddescription
Sensitized cells (EA) bearing different numbers of &42horbar; sites were tested for their ability to generate chemotactic activity from C-EDTA. From the results it can be shown that: 1 the amount of chemotactic activity generated parallels the number of &42horbar; sites bound to the cell surface, 2 all &42horbar; sites clustered around a single hemolytic site are enzymatically active as far as generation of chemotactic activity is concerned, and, 3 no difference can be demonstrated with IgG or IgM antibodies
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1973-06-01 | European Journal of Immunology |