6533b822fe1ef96bd127d5be

RESEARCH PRODUCT

Syndrome démentiel du sujet âgé lié à un traitement par acide valproïque : à propos d’un cas

Patrick ManckoundiaD. RichardPierre PfitzenmeyerOlivier RouaudA. Disson-dautricheBeatrice Tavernier-vidal

subject

DrugValproic Acidmedicine.medical_specialtyPediatricsmedicine.drug_classbusiness.industrymedia_common.quotation_subjectmedicine.medical_treatmentGastroenterologyMood stabilizermedicine.diseaseSurgeryEpilepsyAnticonvulsantIschemic strokeInternal MedicinemedicineDementiabusinessAdverse effectmedicine.drugmedia_common

description

In addition to the usual adverse effects, the chronic use of the valproic acid can entail dementia syndrome. We describe the case of a 68-year-old woman who had presented a dementia syndrome due to the use of valproic acid for one year. This drug was prescribed in order to prevent a potential convulsive crisis after an ischemic stroke in a patient who did not have a history of epilepsy. This case shows that each clinician must be careful about all medications consumed by the patient in the face of cognitive disorders.

https://doi.org/10.1016/j.revmed.2008.01.016