6533b822fe1ef96bd127d62f
RESEARCH PRODUCT
Cell Specific Targeting of Multifunctional γ-Fe2O3 Nanoparticles Through Surface Binding of dsDNA
Mohammed Ibrahim ShukoorFilipe NatalioHeinz C. SchröderMuhammad Nawaz TahirWerner E.g. MüllerWolfgang Tremelsubject
chemistry.chemical_classificationMaterials scienceCellMaghemiteNanoparticleNanotechnologyPolymerengineering.materialmedicine.anatomical_structurechemistryCell cultureTLR3engineeringmedicineBiophysicsReceptorImmunostainingdescription
AbstractThe immobilization of polyinosinic-polycytidylic acid [poly(IC)] on ã-Fe2O3 maghemite nanoparticles via the phosphor-amidate route using a multifunctional polymer is reported. The dsRNA coupled nanoparticles were used to visualize the Toll-like (TLR3) receptors at the cell surface. The presence of TLR3 was demonstrated independently in the Caki-1 cell line by RT-PCR and immunostaining techniques
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-01-01 | MRS Proceedings |