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RESEARCH PRODUCT
Fulminant bilateral Haemophilus influenzae keratitis in a patient with hypovitaminosis A treated with contaminated autologous serum
Manuel Díaz-llopisMaria Jesus Lopez-pratsSalvador Garcia-delpechEmpar Sanz-marcoPatricia Udaondosubject
medicine.medical_specialtyLeukomaCorneal Infectionbiologygenetic structuresbusiness.industryFulminantPerforation (oil well)Hypovitaminosis ACase Reportmedicine.diseasemedicine.disease_causeAutologous serumbiology.organism_classificationHaemophilus influenzaeeye diseasesSurgeryHaemophilus influenzaeKeratitisOphthalmologymedicinehypovitaminosis Abilateral infectious ulcerssense organsbusinessdescription
We report on a patient with hypovitaminosis A treated with autologous serum (AS) who had bilateral infectious ulcers positive for Haemophilus influenzae. The patient suffered a perforation of his right eye and total healing of his left eye with a residual leukoma. In cases of severe malnutrition, serum levels of vitamins and bacteriostatic and growth factors are reduced, so AS would not only be ineffective but also increase the risk of secondary corneal infection. The prophylactic use of a topical antibiotic would be useful in treatment with AS, especially in patients who do not use and adequately store the eye drops, as in our patient.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-01-01 | Clinical Ophthalmology (Auckland, N.Z.) |