6533b822fe1ef96bd127d952

RESEARCH PRODUCT

The Microbiome Studies in Metabolic Diseases have Advanced but are Poorly Standardized and Lack a Mechanistic Perspective

subject

description

Copyright: © 2014 Pekkala S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. During the last decades hundreds of studies have reported the association of Gut Microbiota (GM) with obesity and related metabolic disorders [1]. However, recently the microbiome studies were criticized about the lack of skepticism [2]. The author of the article questioned the role of GM in different diseases and asked whether the detected differences between the subjects biologically matter? We do believe that the role of microbiota in metabolic diseases is true. The impact of GM on human health should not be surprising since our gut shapes up the symbiotic habitat for at least 100 trillion microbial cells that count up to 100-fold more genes than our genome [1].