6533b823fe1ef96bd127e1c6
RESEARCH PRODUCT
Electrochemical synthesis of carbazoles by dehydrogenative coupling reaction
Valentina M. BreisingSiegfried R. WaldvogelDieter SchollmeyerNiclas SchuppAnton Kehlsubject
Green chemistry540 Chemistry and allied sciencesDeblocking filterSupporting electrolyteRadicalSustainable Chemistry010402 general chemistryElectrochemistry01 natural sciencesCatalysisCoupling reactionNC couplingProtecting groupgreen chemistry010405 organic chemistryChemistryCommunicationOrganic Chemistryheterocyclic chemistryGeneral ChemistryCombinatorial chemistryCommunications0104 chemical sciencesAnodecarbazoleselectrochemistry540 Chemiedescription
Abstract A constant current protocol, employing undivided cells, a remarkably low supporting electrolyte concentration, inexpensive electrode materials, and a straightforward precursor synthesis enabling a novel access to N‐protected carbazoles by anodic N,C bond formation using directly generated amidyl radicals is reported. Scalability of the reaction is demonstrated and an easy deblocking of the benzoyl protecting group is presented.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-10-29 |