6533b823fe1ef96bd127e2c1
RESEARCH PRODUCT
A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial
Valentina IsettaMiguel A. NegrínCarmen Monasterio PonsaJuan F. MasaNuria FeuAinhoa ÁLvarezFrancisco Campos RodríguezConcepción RuizJorge AbadFrancisco J. Vázquez-poloRamon Farré VenturaMarina Galdeano LozanoPatricia LloberesCristina EmbidMónica De La PeñaJavier PuertasMireia Dalmases CleriesNeus SalordJaime CorralBernabé JuradoCarmen LeónCarlos EgeaAida MuñozOlga Parra OrdazRoser CambrodiMaría Martel-escobarMeritxell ArquéJosé Ma. Montserrat CanalSpanish Sleep Networksubject
Pulmonary and Respiratory MedicineMaleTelemedicinemedicine.medical_specialtyEpidemiologymedicine.medical_treatmentCost-Benefit Analysislaw.inventionIndirect costsClinical trialsQuality of lifeRandomized controlled triallawmedicineHumansContinuous positive airway pressureProspective StudiesDisease management (health)EpidemiologiaTelecommunication in medicineSleep apnea syndromesPrimary health careSleep Apnea ObstructiveContinuous Positive Airway Pressurebusiness.industryDisease ManagementBayes TheoremCost-effectiveness analysisSíndromes d'apnea del sonMiddle AgedTelemedicinenervous system diseasesrespiratory tract diseasesClinical trialAtenció primàriaPhysical therapyQuality of LifePatient ComplianceFemalebusinessSleepFollow-Up StudiesTelecomunicació en medicinaAssaigs clínicsdescription
Background Compliance with continuous positive airway pressure (CPAP) therapy is essential in patients with obstructive sleep apnoea (OSA), but adequate control is not always possible. This is clinically important because CPAP can reverse the morbidity and mortality associated with OSA. Telemedicine, with support provided via a web platform and video conferences, could represent a cost-effective alternative to standard care management. Aim To assess the telemedicine impact on treatment compliance, cost-effectiveness and improvement in quality of life (QoL) when compared with traditional face-to-face follow-up. Methods A randomised controlled trial was performed to compare a telemedicine-based CPAP follow-up strategy with standard face-to-face management. Consecutive OSA patients requiring CPAP treatment, with sufficient internet skills and who agreed to participate, were enrolled. They were followed-up at 1, 3 and 6 months and answered surveys about sleep, CPAP side effects and lifestyle. We compared CPAP compliance, cost-effectiveness and QoL between the beginning and the end of the study. A Bayesian cost-effectiveness analysis with non-informative priors was performed. Results We randomised 139 patients. At 6 months, we found similar levels of CPAP compliance, and improved daytime sleepiness, QoL, side effects and degree of satisfaction in both groups. Despite requiring more visits, the telemedicine group was more cost-effective: costs were lower and differences in effectiveness were not relevant. Conclusions A telemedicine-based strategy for the follow-up of CPAP treatment in patients with OSA was as effective as standard hospital-based care in terms of CPAP compliance and symptom improvement, with comparable side effects and satisfaction rates. The telemedicine-based strategy had lower total costs due to savings on transport and less lost productivity (indirect costs). Trial register number NCT01716676.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-08-26 |