IL GENE PCSK9: UN NUOVO GENE IMPLICATO NEL CONTROLLO DELLA COLESTEROLEMIA

6533b823fe1ef96bd127e726

RESEARCH PRODUCT

IL GENE PCSK9: UN NUOVO GENE IMPLICATO NEL CONTROLLO DELLA COLESTEROLEMIA

Angelo Baldassare Cefalu'Salvatore Amato Emanuela Fertitta Francesca Fayer Vincenza Valenti Maria Concetta Gueli Di Blasi U Pagano M Nardi I Gaspare Cusumano Paolo Gulotta Alessandro Raffa Tiziana Doveri Maurizio Averna

subject

Settore MED/09 - Medicina Interna Cholesterolemia

description

The distribution of cholesterol plasma is regulated by complex interactions between genes and environmental factors. Mutations of PCSK9 gene seem to modulate the levels of LDL-C. Mutations of PCSK9 gene with gain of function are associated to hypercholesterolemia and mutations with loss of function determine hypocholesterolemia.

year	journal	country	edition	language
2007-01-01

http://hdl.handle.net/10447/15179

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