6533b823fe1ef96bd127e93a
RESEARCH PRODUCT
ChemInform Abstract: A Catalytic Highly Enantioselective Direct Synthesis of 2-Bromo-2-nitroalkan-1-ols Through a Henry Reaction.
José R. PedroVictor Hernandez‐olmosGonzalo Blaysubject
Addition reactionNitroaldol reactionChemistryBromonitromethaneCondensationEnantioselective synthesisOrganic chemistrychemistry.chemical_elementGeneral MedicineCopperPyridine ligandCatalysisdescription
Highly enantiomerically enriched 2-bromo-2-nitroalkan-1-ols are prepared by direct condensation of aliphatic and aromatic aldehydes with bromonitromethane in the presence of a catalytic amount of copper(II) acetate and a C1-symmetric camphor-derived amino pyridine ligand.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-02-24 | ChemInform |