6533b823fe1ef96bd127e955

RESEARCH PRODUCT

One-pot synthesis of polyaza[n]naphthalenophanes and polyaza[n]anthracenophanes

Juan F. MiravetM. Isabel BurgueteSantiago V. LuisBeatriu EscuderManuel QuerolEnrique García-españa

subject

ChemistryOrganic ChemistryDrug DiscoveryOne-pot synthesisBiochemistryMedicinal chemistry

description

Abstract Pernosylated polyaza[n]cyclophanes 13–20 were prepared by a Richman-Atkins modified methodology. Deprotection under mild conditions gave polyaza[n]cyclophanes 21–28 . This methodology allows for the preparation of cyclophanes containing labile C-N bonds.

https://doi.org/10.1016/s0040-4039(98)00587-5