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RESEARCH PRODUCT
OXA-163-Producing Klebsiella pneumoniae in Cairo, Egypt, in 2009 and 2010
Ramadan A. El-domanyCaterina MamminaAurora AleoMohammed O. AbdelazizTeresa FascianaCelestino Bonurasubject
AdultDNA BacterialMaleMicrobiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaOXA-163EpidemiologyKlebsiella pneumoniaemedicine.drug_classMolecular Sequence DataCephalosporinSettore MED/42 - Igiene Generale E Applicatabeta-Lactam Resistancebeta-LactamasesTravel abroadMicrobiologyAntibiotic resistancepolycyclic compoundsmedicineHumansOXA-163; Klebsiella pneumoniaebiologyGeographic areaHydrolysisSequence Analysis DNAKlebsiella infectionsbiochemical phenomena metabolism and nutritionbiology.organism_classificationVirologyAnti-Bacterial AgentsCephalosporinsKlebsiella InfectionsKlebsiella pneumoniaeCarbapenemsbacteriaEgyptFemaledescription
ABSTRACT Two genetically unrelated OXA-163-carrying Klebsiella pneumoniae strains were identified from two infection cases in June 2009 and May 2010 in Cairo, Egypt. OXA-163-producing Enterobacteriaceae had been previously reported in Argentina only. Both patients had no history of travel abroad. The emergence of this newly recognized OXA-48-related β-lactamase able to hydrolyze cephalosporins and carbapenems is especially worrying in a geographic area where OXA-48 is endemic and effective surveillance for antibiotic resistance is largely unaffordable.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-07-01 | Journal of Clinical Microbiology |