6533b823fe1ef96bd127ec46
RESEARCH PRODUCT
Proteomics in antitumor research
Sandra Kraljević PavelićRiccardo AlessandroGiacomo De LeoMirela SedićSimona Fontanasubject
proteomika; tumori; proteinski čipovi; 2DE; masena spektrometrijaCell typeshotgun approachesCellEarly detectionCancerComputational biologyBiologyProteomicsBioinformaticsmedicine.diseasemedicine.anatomical_structureSettore BIO/13 - Biologia ApplicataDrug DiscoveryCancer managementCancer cellmedicineMolecular MedicineProtein networkClassical gel-base approachdescription
Proteins are the molecular players of fine-tuned regulatory pathways that underlie the behavior of any cell type. Derangement of this wide protein circuitry has a profound effect on cell life and ultimately contributes to the development of diseases such as cancer. New proteomic technologies are rapidly evolving to define and characterize the nodes of this altered protein network, both inside and outside cancer cells. Hopefully, these technologies will become user-friendly laboratory tools to improve cancer management from early detection to the development of rational and patient-tailored therapeutic strategies.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-12-01 |