ChemInform Abstract: Efficient Synthesis of Quaternary and P-Stereogenic Phosphonium Triflates.

6533b823fe1ef96bd127f442

RESEARCH PRODUCT

ChemInform Abstract: Efficient Synthesis of Quaternary and P-Stereogenic Phosphonium Triflates.

Emmanuelle Rémond Arnaud Tessier Frédéric R. Leroux Sylvain Jugé Jerome Bayardon

subject

chemistry.chemical_compound General method chemistry Trimethylsilyl Aryl Organic chemistry General Medicine Phosphonium Aryne Stereocenter

description

An efficient and general method for the preparation of achiral and chiral phosphonium salts is reported. This synthesis is based on the quaternization of phosphines and their derivatives with arynes generated in situ from 2-(trimethylsilyl)aryl triflates. This methodology is successfully applied to the synthesis of new valuable P-stereogenic phosphonium triflates.

year	journal	country	edition	language
2010-07-23	ChemInform

https://doi.org/10.1002/chin.201032183

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