6533b823fe1ef96bd127f4e1
RESEARCH PRODUCT
New Steroidal Alkaloids from Solanum Hypomalacophyllum
Alida Pérez ColmenaresAnne Claire Mitaine-offerLaurent PouységuMarie-aleth Lacaille-duboisAlfredo UsubillagaThomas PaululatStéphane QuideauLibia AlarcónLuis B. Rojassubject
PharmacologybiologyPlant compositionChemical structurePlant ScienceGeneral Medicinebiology.organism_classificationchemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoveryBotanySolanumChemical compositionOleanolic acidSolanaceaedescription
Two new steroidal alkaloids (1-2) have been isolated from the leaves and roots of Solanum hypomalacophyllum Bitter, respectively. Their structures have been elucidated as deacetoxysolaphyllidine-3- O-β-D-glucopyranoside (1) and 4-keto-5,6-dihydro-(20 S)-verazine (2). Furthermore, two known steroidal alkaloids, 20 R-verazine and 20 S-verazine, and the common secondary metabolites oleanolic acid and β-sitosterol were isolated from the roots, whereas deacetoxysolaphyllidine was obtained from the leaves.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-11-01 | Natural Product Communications |