6533b823fe1ef96bd127f4ee

RESEARCH PRODUCT

Molecular epidemiology of astrovirus infection in Italian children with gastroenteritis

S De GraziaG. M. GiammancoC ColombaL BoninaAntonio CascioS. Arista

subject

MaleMicrobiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaSettore MED/17 - Malattie InfettiveVirusAstrovirusCell LineAstroviruschildrenAstroviridae InfectionsmedicineHumansTypingPhylogenyMolecular EpidemiologyMolecular epidemiologybiologybusiness.industrytypingInfantGeneral MedicineHuman astrovirusbiology.organism_classificationVirologyGastroenteritisMolecular Epidemiology* Astroviridae Infections/*epidemiology Gastroenteritis/*epidemiology Mamastrovirus/*genetics Astroviridae Infections/virologydiarrhoeaDiarrheaInfectious DiseasesItalyChild PreschoolImmunologyastrovirus epidemiologyFemaleepidemiologymedicine.symptombusinessMamastrovirus

description

A 1-year study involving 157 gastroenteritis samples was conducted to investigate the role of human astrovirus, (HAstV) as a cause of gastroenteritis in Italian children aged < 2 years. The overall incidence of HAstV was 3.1%. Most cases occurred between March and May, and four of the five isolates were of the HAstV-1 type, the other being HAstV-3. Analysis of genetic variability showed that the three HAstV-1 isolates collected in 2000 clustered together, but separately from the 1999 isolate. The results indicated that HAstV should be considered as a potential diarrhoeal pathogen in Italian children. © 2004 Copyright by the European Society of Clinical Microbiology and Infectious Diseases

10.1111/j.1469-0691.2004.00995.xhttp://hdl.handle.net/10447/1948