P-56LOCAL BLOCKADE OF THE MU OPIOID RECEPTOR REVEALS THE DUAL MOTOR EFFECT OF ETHANOL IN pVTA

6533b824fe1ef96bd1280957

RESEARCH PRODUCT

P-56LOCAL BLOCKADE OF THE MU OPIOID RECEPTOR REVEALS THE DUAL MOTOR EFFECT OF ETHANOL IN pVTA

Yolanda Campos-jurado Lucía Hipólito Alejandro Orrico Lucía Martí-prats M. J. Sánchez-catalán F. B. Gosálbez M. J. Cano-cebrián Teodoro Zornoza

subject

Ethanol Chemistry General Medicine Inhibitory postsynaptic potential Blockade Ventral tegmental area chemistry.chemical_compound Electrophysiology medicine.anatomical_structure Dopamine medicine Excitatory postsynaptic potential μ-opioid receptor Neuroscience medicine.drug

description

Previous electrophysiological and behavioral data have revealed the existence of ethanol opposite effects (excitatory and inhibitory) on the posterior ventral tegmental area (pVTA) dopamine (DA) neurons activity. These activating and depressing effects of ethanol could be the result of two concurrent and opposing mechanisms, one increasing and the other reducing GABA release …

year	journal	country	edition	language
2015-09-01	Alcohol and Alcoholism

https://doi.org/10.1093/alcalc/agv080.56

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