0000000000547724

AUTHOR

F. B. Gosálbez

showing 2 related works from this author

P-56LOCAL BLOCKADE OF THE MU OPIOID RECEPTOR REVEALS THE DUAL MOTOR EFFECT OF ETHANOL IN pVTA

2015

Previous electrophysiological and behavioral data have revealed the existence of ethanol opposite effects (excitatory and inhibitory) on the posterior ventral tegmental area (pVTA) dopamine (DA) neurons activity. These activating and depressing effects of ethanol could be the result of two concurrent and opposing mechanisms, one increasing and the other reducing GABA release …

EthanolChemistryGeneral MedicineInhibitory postsynaptic potentialBlockadeVentral tegmental areachemistry.chemical_compoundElectrophysiologymedicine.anatomical_structureDopaminemedicineExcitatory postsynaptic potentialμ-opioid receptorNeurosciencemedicine.drugAlcohol and Alcoholism
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P-77D-PENICILLAMINE, A POTENTIAL ETHANOL ANTI-RELAPSE DRUG, DOES NOT REDUCE THE VOLUNTARY ETHANOL INTAKE IN LONG-TERM EXPERIENCED RATS

2015

Experimental evidence has demonstrated that the reinforcing effects of ethanol crucially depend on the brain formation of acetaldehyde (ACD). Rationally supported by this basis, we previously evaluated a novel strategy to prevent relapse in alcoholism based on chemical ACD inactivation using D-Penicillamine (DP). Under our experimental …

DrugEthanolbusiness.industrymedia_common.quotation_subjectPenicillamineAcetaldehydeGeneral MedicinePharmacologychemistry.chemical_compoundchemistryBiochemistrymedicineEthanol intakebusinessmedicine.drugmedia_commonAlcohol and Alcoholism
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