Sleep in children with autistic spectrum disorder: a questionnaire and polysomnographic study.

6533b824fe1ef96bd12809d3

RESEARCH PRODUCT

Sleep in children with autistic spectrum disorder: a questionnaire and polysomnographic study.

Raffaele Ferri Oliviero Bruni Mario Giovanni Terzano Alessia Trovato Michele Roccella Arianna Smerieri Elisabetta Verrillo Silvia Miano Maurizio Elia

subject

Male medicine.medical_specialty Adolescent cyclic alternating pattern Polysomnography Sleep REM Polysomnography Comorbidity Audiology Non-rapid eye movement sleep actigraphy polysomnography Enuresis Sleep Disorders Circadian Rhythm Surveys and Questionnaires mental disorders Activities of Daily Living medicine Humans Autistic Disorder Parent-Child Relations Child Sleep disorder Sleep Stages Sleep stage medicine.diagnostic_test autistic spectrum disorder Actigraphy General Medicine medicine.disease Comorbidity Sleep in non-human animals Settore MED/39 - Neuropsichiatria Infantile sleep questionnaire actigraphy; actigraphy polysomnography; autistic spectrum disorder; cyclic alternating pattern; polysomnography; sleep questionnaire; sleep stages Logistic Models Child Preschool Physical therapy Female Sleep Stages medicine.symptom Psychology actigraphy

description

Abstract Objective To evaluate sleep in children with autistic spectrum disorder (ASD) by means of sleep questionnaires and polysomnography; moreover, to analyze their cyclic alternating pattern (CAP). Methods Thirty-one patients with ASD (28 males, 3 females, aged 3.7–19 years) and age-matched normal controls were included. ASD children were evaluated by a standard sleep questionnaire that consisted of 45 items in a Likert-type scale covering several areas of sleep disorders and by overnight polysomnography in the sleep laboratory after one adaptation night. Results The questionnaire results showed that parents of ASD children reported a high prevalence of disorders of initiating and maintaining sleep, enuresis, repetitive behavior when falling asleep, and daytime sleepiness. Polysomnographically, ASD children showed reduced time in bed, total sleep time, sleep period time and rapid eye movement (REM) latency. ASD subjects had a CAP rate during slow-wave sleep (SWS) lower than normal controls, together with a lower percentage of A1 subtypes. Conclusions ASD children questionnaires showed a higher percentage of disorders of initiating and maintaining sleep than normal controls; this was not completely confirmed by sleep staging. CAP measures showed subtle alterations of NREM sleep which could be detected with an appropriate methodology of analysis. The reduction of A1 subtypes during SWS might play a role in the impairment of cognitive functioning in these subjects.

year	journal	country	edition	language
2007-01-01	Sleep medicine

10.1016/j.sleep.2007.01.014 https://pubmed.ncbi.nlm.nih.gov/17728182