6533b824fe1ef96bd1280a38
RESEARCH PRODUCT
Strain-Promoted Cycloaddition of Cyclopropenes with o-Quinones : A Rapid Click Reaction
Rickdeb SenDigvijay GahtoryHan ZuilhofHan ZuilhofHan ZuilhofAndriy R. KuzmynJorge Escorihuelasubject
KineticsClick Chemistry | Hot Paper010402 general chemistryPolymer brushO quinones01 natural sciencesCatalysisReaccions químiquesMonolayerotorhinolaryngologic diseasesMetal-free click reactionsVLAGchemistry.chemical_classificationMonolayersMass spectrometry010405 organic chemistryChemistryCommunicationOrganic ChemistryGeneral MedicineGeneral ChemistryPolymerCombinatorial chemistryOrganische ChemieCycloadditionCommunications0104 chemical sciencesKineticsClick chemistrySurface modificationPolymer brushesQuímica orgànicahuman activitiesdescription
Abstract Novel click reactions are of continued interest in fields as diverse as bio‐conjugation, polymer science and surface chemistry. Qualification as a proper “click” reaction requires stringent criteria, including fast kinetics and high conversion, to be met. Herein, we report a novel strain‐promoted cycloaddition between cyclopropenes and o‐quinones in solution and on a surface. We demonstrate the “click character” of the reaction in solution and on surfaces for both monolayer and polymer brush functionalization.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-04-01 | Angewandte Chemie - International Edition |