6533b824fe1ef96bd1280b1f
RESEARCH PRODUCT
Prostaglandin production by human polymorphnuclear leucocytes during phagocytosis in vitro.
L BonaseraC ToloneG. ToloneM Braisubject
PharmacologyPolymorphonuclear leukocyteNeutrophilsPhagocytosismedicine.medical_treatmentProstaglandins EZymosanProstaglandin productionZymosanProstaglandinCell BiologyIn Vitro TechniquesIn vitroMicrobiologyCellular and Molecular Neurosciencechemistry.chemical_compoundchemistryPhagocytosisImmunologymedicineMolecular MedicineHumansMolecular BiologyProstaglandin Edescription
Human polymorphonuclear leukocytes were found to be able to synthetize and release substantial amounts of PGE2' when stimulated by a phagocytic stimulus such as zymosan particles coated with complement. Hydrocortisone, at a concentration of 10(-5) M, which proved to be effective in other biological systems, failed to inhibit phagocytosis and PG release.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1977-07-01 | Experientia |