6533b824fe1ef96bd1280bbe

RESEARCH PRODUCT

Characterization of Acinetobacter baumannii from intensive care units and home care patients in Palermo, Italy.

Aurora AleoConcetta SodanoCinzia CalàDaniela Maria PalmaTma FascianaAnna GiammancoM. LabisiS. DistefanoCelestino BonuraCaterina MamminaA. Di BenedettoMaria Concetta CataldoGiuseppe Caputo

subject

Microbiology (medical)Acinetobacter baumanniimedicine.medical_specialtyPediatricsSettore MED/07 - Microbiologia E Microbiologia ClinicaGenotypeDrug resistanceMicrobial Sensitivity Testshome care patientsintensive care unitbeta-Lactamaseslaw.inventionlawmultidrug resistanceIntensive careInternal medicineDrug Resistance Multiple BacterialGenotypepolycyclic compoundsmedicinePulsed-field gel electrophoresisCluster AnalysisHumansCross Infectionbiologybusiness.industryGeneral Medicinebiochemical phenomena metabolism and nutritionbacterial infections and mycosesbiology.organism_classificationIntensive care unitHome Care ServicesAcinetobacter baumanniiAnti-Bacterial AgentsElectrophoresis Gel Pulsed-FieldCommunity-Acquired InfectionsMolecular TypingIntensive Care UnitsInfectious DiseasesItalyColistinMultilocus sequence typingepidemiologybusinesshome caremedicine.drugAcinetobacter InfectionsMultilocus Sequence Typing

description

AbstractIn this study 45 isolates of Acinetobacter baumannii identified from patients in intensive care units of three different hospitals and from pressure ulcers in home care patients in Palermo, Italy, during a 3-month period in 2010, were characterized. All isolates were resistant to at least three classes of antibiotics, but susceptible to colistin and tygecycline. Forty isolates were non-susceptible to carbapenems. Eighteen and two isolates, respectively, carried the blaOXA-23-like and the blaOXA-58-like genes. One strain carried the VIM-4 gene. Six major rep-PCR subtype clusters were defined, including isolates from different hospitals or home care patients. The sequence type/pulsed field gel electrophoresis group ST2/A included 33 isolates, and ST78/B the remaining 12. ST2 clone proved to be predominant, but a frequent involvement of the ST78 clone was evident.

yearjournalcountryeditionlanguage
2011-11-01
10.1111/j.1469-0691.2011.03654.x.http://hdl.handle.net/10447/64903