6533b824fe1ef96bd1280c89
RESEARCH PRODUCT
The occurrence of serological H-Y antigen (Sxs antigen) in the diandric protogynous wrasse, Coris julis (L.) (Labridae, Teleostei)
Cecilia EbenspergerUlrich WolfRudolf ReinbothAntonia Mayerovásubject
Cytotoxicity ImmunologicMaleCancer Researchmedicine.drug_classH-Y AntigenCorisZoologyEnzyme-Linked Immunosorbent AssayBiologyAntigenHermaphroditeTestismedicineAnimalsTestosteroneMolecular BiologyDrug ImplantsH-Y antigenOvaryFishesCell BiologyAnatomySex reversalAndrogenbiology.organism_classificationSpermatogoniaWrasseOocytesFemaleHeterogametic sexDevelopmental Biologydescription
Abstract The serological sex-specific (Sxs) antigen (previously called ‘H-Y antigen’) has been shown, in various vertebrate species ranging from fish to mammals, to be characteristic of the heterogametic sex. We studied a protogynous hermaphrodite, Coris julis , in order to examine whether the change of a female to a secondary male also involves a change in the Sxs-antigen phenotype. The (homogametic) females of this species were found to be Sxs negative, while both primary and secondary males were Sxs positive. This was true not only for gonads but also for nongo-nadal tissues. The administration of androgen to females is known to cause sex inversion in this species; we were able to demonstrate this again at the histological level, and found that androgen results in a Sxs positive phenotype in all tissues studied (gonads, spleen, muscle). We propose that androgen is responsible, directly or indirectly, for the occurrence of the Sxs antigen.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1987-04-01 | Differentiation |