6533b824fe1ef96bd1281504

RESEARCH PRODUCT

Glucose influence on the production of T-2 toxin by Fusarium sporotrichioides

Jordi MañesJesús BlesaGiuseppe MecaJosé Miguel SorianoAlberto RitieniJosep Rubert

subject

FusariumPDATrichotheceneToxicologymedicine.disease_causeMicrobiologymycotoxinchemistry.chemical_compoundFusariumTandem Mass SpectrometryT-2 toxinmedicineMycotoxinfermentationChromatography High Pressure LiquidbiologyStrain (chemistry)ToxinFungi imperfectibiology.organism_classificationFusarium sporotrichioidesLC-MSGlucosechemistryCulture Media ConditionedFusarium sporotrichioidesFermentationTrichothecenes

description

Toxigenic isolate of Fusarium sporotrichioides was tested for the T-2 toxin production on PDA plates during 10 days under various glucose concentrations. T-2 toxin was determined by LC-MS and confirmed with LC-MS/MS. This analytical method has been applied, for the first time, to an extensive study of T-2 accumulation. Results showed that the production of this mycotoxin is directly correlated to the concentration of glucose present in the medium. Concentrations of T-2 toxin produced by the strain of F. sporotrichioides ranged from 0 to 1.45 mg/kg. The better T-2 production was evidenced in the fermentation operated with 20% of glucose.

yearjournalcountryeditionlanguage
2010-01-01
10.1016/j.toxicon.2010.01.005https://research.wur.nl/en/publications/glucose-influence-on-the-production-of-t-2-toxin-by-fusarium-spor