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RESEARCH PRODUCT
Soft Tissue Response to Titanium Abutments with Different Surface Treatment: Preliminary Histologic Report of a Randomized Controlled Trial
David PeñarrochaAnnalisa MazzoniJan Friedrich DehnerVittorio ChecchiLuigi CanulloLorenzo Breschisubject
MaleGenetics and Molecular Biology (all)Pathologymedicine.medical_specialtyPlasma GasesArticle SubjectCleaning methodsImmunology and Microbiology (all)Statistical differencelcsh:MedicineDental AbutmentsBiochemistryGeneral Biochemistry Genetics and Molecular BiologySoft Tissue Responselaw.inventionPlasma Gase03 medical and health sciences0302 clinical medicineRandomized controlled trialDental AbutmentslawCollagen; Female; Humans; Male; Middle Aged; Mouth; Plasma Gases; Titanium; Wound Healing; Dental AbutmentsHumansMedicineddc:610TitaniumMouthWound HealingDental AbutmentBiochemistry Genetics and Molecular Biology (all)General Immunology and Microbiologybusiness.industrySignificant differencelcsh:RSoft tissue030206 dentistryGeneral MedicineMiddle AgedClinical StudyFemaleCollagenWound healingbusinessHuman030215 immunologyBiochemistry; Genetics and Molecular Biology (all); Immunology and Microbiology (all)description
The aim of this preliminary prospective RCT was to histologically evaluate peri-implant soft tissues around titanium abutments treated using different cleaning methods. Sixteen patients were randomized into three groups: laboratory customized abutments underwent Plasma of Argon treatment (Plasma Group), laboratory customized abutments underwent cleaning by steam (Steam Group), and abutments were used as they came from industry (Control Group). Seven days after the second surgery, soft tissues around abutments were harvested. Samples were histologically analyzed. Soft tissues surrounding Plasma Group abutments predominantly showed diffuse chronic infiltrate, almost no acute infiltrate, with presence of few polymorphonuclear neutrophil granulocytes, and a diffuse presence of collagenization bands. Similarly, in Steam Group, the histological analysis showed a high variability of inflammatory expression factors. Tissues harvested from Control Group showed presence of few neutrophil granulocytes, moderate presence of lymphocytes, and diffuse collagenization bands in some sections, while they showed absence of acute infiltrate in 40% of sections. However, no statistical difference was found among the tested groups for each parameter (p>0.05). Within the limit of the present study, results showed no statistically significant difference concerning inflammation and healing tendency between test and control groups.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-01-01 | BioMed Research International |