6533b825fe1ef96bd1281cb7
RESEARCH PRODUCT
FIA-Fluorimetric assembly for the determination of noradrenaline hydrochloride by a solid-phase reactor with immobilized hexacyanoferrate(III)
José Martínez CalatayudSalome Laredo OrtizGustavo A. Rivassubject
chemistry.chemical_compoundChromatographychemistryHydrochlorideCalibration curveReagentSodium sulfateFluorescence spectrometryQuantitative analysis (chemistry)Dosage formFluorescence spectroscopyAnalytical Chemistrydescription
An FIA assembly provided with immobilized hexacyanoferrate(III) is proposed for the fluorimetric determination of noradrenaline hydrochloride. The oxidative reagent is immobilized by means of a strong anion-exchange resin. The FIA manifold is very simple and the calibration graph is linear over the range 0.5–75mgl−1 noradrenaline hydrochloride with an r.s.d of 0.88% (17 replicates) and a sample throughput of 84h−1. Foreign compounds such as NaCl, sucrose, lactose and sodium sulfate caused no significant errors. The procedure is applied to the determination of noradrenaline in a medicinal formulation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1997-03-01 | Mikrochimica Acta |