Tetraaza-2,2′-biphenylophanes: larger is not always more flexible. The role of intramolecular H-bonding in polyazamacrocycles

6533b825fe1ef96bd1281d3e

RESEARCH PRODUCT

Tetraaza-2,2′-biphenylophanes: larger is not always more flexible. The role of intramolecular H-bonding in polyazamacrocycles

Manel Querol Enrique García-españa Santiago V. Luis Laura López M. Isabel Burguete Beatriu Escuder Juan F. Miravet

subject

Molecular dynamics Crystallography Flexibility (anatomy)medicine.anatomical_structure Hydrogen bond Computational chemistry Chemistry Intramolecular force Organic Chemistry Drug Discovery medicine Biochemistry

description

Abstract Intramolecular H-bonding can explain the trends in conformational flexibility for tetraaza-2,2′-biphenylophanes obtained by NMR and molecular dynamics calculations.

year	journal	country	edition	language
2002-03-01	Tetrahedron Letters

https://doi.org/10.1016/s0040-4039(02)00121-1

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