6533b825fe1ef96bd1281fd7

RESEARCH PRODUCT

The control of amygdaloid seizures by the globus pallidus.

V. La GruttaGiuseppe CrescimannoFilippina SorberaGiuseppe Amato

subject

Kainic acidStimulationGlobus PallidusAmygdalaLesionCellular and Molecular Neurosciencechemistry.chemical_compoundSeizuresMedicineAnimalsMolecular BiologyInhibitory effectPharmacologyDecerebrate StateCATSbusiness.industryCell BiologyAmygdalaElectric Stimulationnervous system diseasesmedicine.anatomical_structureGlobus pallidusnervous systemchemistryCatsMolecular Medicinemedicine.symptomCaudate NucleusbusinessNeuroscience

description

Both in acute and chronic cats entopeduncular stimulation inhibits, to a greater extent than caudate activation, focal paroxysmal activity in the ventro-basal complex of the amygdala. Lesion of entopeduncular neurons, by means of kainic acid injection, induces a decrease of the caudate inhibitory effect. It is suggested that neostriatal control of the amygdaloid seizures occurs partly through the globus pallidus.

10.1007/bf01963210https://pubmed.ncbi.nlm.nih.gov/7238745