6533b825fe1ef96bd1282757

RESEARCH PRODUCT

Platelet Signal-Dependent Protein Synthesis

Andrew S. WeyrichStephen M. PrescottGuy A. ZimmermanThomas M. McintyreStephan Lindemann

subject

Adherent plateletCoagulationbusiness.industryImmunologyMedicinePlateletHuman plateletbusinessmedicine.diseaseThrombosis

description

Our understanding of platelet functions has been in evolution since their discovery. Blood platelets were initially observed in the middle of the 19th century by many investigators including Zimmerman in 1860, Schultze in 1865, Osler in 1874, and Hayem in 1878 (1). Studies by Bizzozero (2,3) were the first to recognize the adhesive qualities of platelets, their participation in thrombosis and leukocyte recruitment, and their role in blood coagulation. These monumental findings, which have withstood the test of time, have expanded at a remarkable rate and continue to be the primary focus of investigative research in the platelet arena (4).

yearjournalcountryeditionlanguage
2007-11-10
https://doi.org/10.1007/978-1-59259-917-2_6