6533b825fe1ef96bd128275c

RESEARCH PRODUCT

Serotonin–dopamine interaction: an overview

Giuseppe Di GiovanniVincenzo Di MatteoEnnio Esposito

subject

business.industryDopaminergicSubstantia nigramedicine.diseaseSerotonergicVentral tegmental areamedicine.anatomical_structureDopamineSchizophreniaMedicineSerotoninbusinessNeuroscience5-HT receptormedicine.drug

description

Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviours. Moreover, recent evidence suggests that the dysfunction of dopamine (DA) and serotonin (5-hydroxytriptamine, 5-HT) neurotransmission might underlie the pathophysiology of neuropsychiatric disorders, including depression, schizophrenia, attention deficit hyperactivity disorders, drug abuse, Gilles de la Tourette's syndrome and Parkinson's disease.

yearjournalcountryeditionlanguage
2008-01-01
https://doi.org/10.1016/s0079-6123(08)00901-1