6533b825fe1ef96bd1282a50
RESEARCH PRODUCT
Allergic contact dermatitis: understanding the immune response and potential for targeted therapy using cytokines.
Alexander Enksubject
CD4-Positive T-Lymphocytesmedicine.medical_treatmentT-LymphocytesDiseaseCD8-Positive T-Lymphocytesmedicine.disease_causeLymphocyte ActivationTargeted therapyPathogenesisMiceImmune systemAllergenGeneticsmedicineAnimalsHumansRNA AntisenseAllergic contact dermatitisbusiness.industryDendritic CellsGenetic Therapymedicine.diseaseLangerhans CellsImmunologyDermatitis Allergic ContactMolecular MedicineCytokinesImmune reactionbusinessdescription
Allergic contact dermatitis is the most common job-related disease of the western world. The only available treatments are avoidance of contact with the allergen and the use of potent corticosteroids. Recently, the role of cytokines in the pathogenesis of this disease has been studied and, besides defining the key molecules and basic cellular immune responses responsible for disease development, these studies might help to develop new therapeutic strategies to target cytokines and thereby try to alter or abrogate ongoing immune reactions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1997-10-01 | Molecular medicine today |